Table of Contents
What is Zofran?
Zofran impedes the effects of chemicals in the body that can initiate nausea and vomiting. Its primary use is to prevent nausea and vomiting associated with surgery, cancer chemotherapy, or radiation treatment.
Warnings
The usage of Zofran is contraindicated in individuals concurrently using apomorphine (Apokyn) and those allergic to ondansetron or similar medications such as dolasetron (Anzemet), granisetron (Kytril), or palonosetron (Aloxi). Notably, Zofran orally disintegrating tablets may contain phenylalanine, making it crucial for individuals with phenylketonuria (PKU) to inform their doctor. Serious side effects, including vision issues, slow heart rate, breathing difficulties, and others, warrant immediate medical attention. Ondansetron may affect cognitive functions, necessitating caution during activities requiring alertness.
Before Taking this Medicine
Individuals with liver disease, electrolyte imbalances, congestive heart failure, a history of long QT syndrome, or a digestive tract blockage should inform their doctor before using Zofran. Pregnant individuals should disclose their condition to their doctor, as the impact on unborn babies is not fully understood. Breastfeeding while using Zofran requires consideration, and the medication is not approved for those under 4 years old.
Related/Similar Drugs
Other drugs related to Zofran include ondansetron, hydroxyzine, lorazepam, dexamethasone, olanzapine, promethazine, and Ativan.
How should I take Zofran?
Zofran should be taken precisely as prescribed, with dosage instructions varying based on the situation. The first dose is typically administered before surgery, chemotherapy, or radiation treatment. Zofran can be taken with or without food. The orally disintegrating tablet should be handled with dry hands and allowed to dissolve in the mouth without chewing.
What Happens if I Miss a Dose?
In case of a missed dose, it should be taken as soon as remembered. However, if it’s nearing the next scheduled dose, skipping the missed one is advised. Doubling up on doses should be avoided.
What Happens if I Overdose?
In the event of an overdose, immediate medical attention is necessary, with symptoms potentially including sudden vision loss, severe constipation, lightheadedness, or fainting.
What to Avoid
Zofran may affect cognitive functions, so activities requiring alertness, such as driving, should be approached cautiously. Additionally, potential drug interactions, especially with antibiotics, antidepressants, and others, should be communicated to the doctor.
Zofran Side Effects
Emergency medical help is required for signs of an allergic reaction, severe constipation, headaches with chest pain and dizziness, blurred vision, and high serotonin levels. Common side effects include diarrhea or constipation, headaches, drowsiness, and fatigue.
What Other Drugs Will Affect Zofran?
Zofran can induce serious heart problems when used with certain medications. Communication with the doctor regarding all current and newly initiated medications, including antidepressants and narcotics, is essential to avoid potential interactions.