Zopiclone

 


What is zopiclone?


Zopiclone is a medication designed to address insomnia, a sleep disorder. Classified as a non-benzodiazepine hypnotic, it differs structurally from benzodiazepine sedative hypnotics like triazolam (Halcion) but shares similar benefits and side effects.

What is zopiclone used for?


Zopiclone is utilized for the short-term (7-14 days) treatment of insomnia in adults, helping with difficulties such as falling asleep, waking in the middle of the night, waking too early, or sleep problems related to mood or mental health issues. Long-term use beyond 4 weeks is discouraged due to the risk of tolerance, dependence, withdrawal, and rebound insomnia.

Important information


This section highlights crucial information about zopiclone, emphasizing potential serious side effects. It addresses the risk of abuse, physical and psychological dependence, and interactions with opioids. Additionally, it notes the potential for suicidal ideation, the importance of ensuring uninterrupted sleep, and the occurrence of unusual behaviors during sleep.

Who should not take zopiclone?


Clear criteria are provided regarding individuals who should refrain from taking zopiclone, including those with allergies to the medication, severe muscle weakness (myasthenia gravis), respiratory failure, sleep apnea, severe liver problems, and those under the age of 18. It also cautions against usage in individuals with a history of sleepwalking or engaging in activities while not fully awake.

What should I tell my doctor before taking zopiclone?


Patients are advised to communicate various medical conditions, such as liver or kidney problems, breathing issues, mental disorders, substance abuse history, and recent use of similar medications. This section provides a comprehensive checklist for patients to discuss with their healthcare providers before starting zopiclone..

How should I take zopiclone?


Detailed instructions on proper zopiclone administration are provided, including dosage, swallowing the tablet whole, and considerations for specific populations such as the elderly or those with liver or kidney problems. The importance of a full night’s sleep and the gradual cessation of treatment are also emphasized.

What happens if I miss a dose?


Guidance on missed doses is provided, advising patients to skip the missed dose and not take two doses simultaneously.

What happens if I overdose?


Potential effects of overdose are detailed, including symptoms such as drowsiness, confusion, coma, hypotonia, dizziness, and respiratory depression. Immediate medical attention is recommended in case of overdose.

What should I avoid while taking zopiclone?


Patients are cautioned against alcohol consumption while taking zopiclone and are advised to refrain from operating dangerous machinery or driving for 12 hours after taking the medication.

Dosing information


Specific dosing information is provided for adults, the elderly, individuals with liver or kidney problems, and children. Detailed recommendations for different patient groups are presented.

What are the side effects of zopiclone?


The section details potential side effects, categorizing them as serious, rare, uncommon, and common. It covers a range of effects, including allergic reactions, poor memory, hallucinations, falling, mood changes, drowsiness, and others.

Interactions


Information on drug interactions is presented, highlighting medications that may enhance or decrease the effectiveness of zopiclone. Special attention is given to opioids, antibiotics, antifungal agents, and other drugs that may impact zopiclone’s effects.

Pregnancy and breastfeeding


Guidance regarding zopiclone use during pregnancy and breastfeeding is provided, cautioning against usage due to potential risks to the baby. Specific effects on fetal movement, heart rate, muscle weakness, and withdrawal symptoms are mentioned.

Storage


Clear instructions on how to store zopiclone, including temperature considerations and precautions to keep it away from children, are provided.

What are the ingredients in zopiclone?


The active and inactive ingredients in zopiclone are listed, specifying the components present in different formulations of the medication.